Structure of PDB 4hab Chain C

Receptor sequence
>4habC (length=187) Species: 9606 (Homo sapiens) [Search protein sequence]
HLSDMLQQLHSVNASKEDIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFN
DSTRLILYNDGDSLQYIERDGTESYLTNSLMKKITLLKYFRNYMSEHLLK
AGANITPRELPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLVT
YIDEKRDFRTYRLSLLCKELASRLRYARTMVDKLLSS
3D structure
PDB4hab Development of cyclic peptomer inhibitors targeting the polo-box domain of polo-like kinase 1.
ChainC
Resolution2.65 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.11.21: polo kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C W414 V415 D416 Y417 H489 L490 L491 R516 H538 W27 V28 D29 Y30 H97 L98 L99 R118 H140
External links
PDB RCSB:4hab, PDBe:4hab, PDBj:4hab
PDBsum4hab
PubMed23498919
UniProtP53350|PLK1_HUMAN Serine/threonine-protein kinase PLK1 (Gene Name=PLK1)

[Back to BioLiP]