Structure of PDB 4gr5 Chain C

Receptor sequence
>4gr5C (length=457) Species: 47763 (Streptomyces lydicus) [Search protein sequence]
SNPFEEYDGGHVVLTDALGRHSLWPAGIAVPAGWSVRHGTDSREGCLAHI
EHHWTDLRPTGPAVERAPAGACVHELFEAQAARAPDAVALLHEADELTYG
ALNERANRLAHRLVGLGVAPGTLVGVHLERGFDMVVALLAVLKAGGGYTM
LDPQFPVERLALSLEDTGAPLLVTSRPLSGRLTGTTTLYVEDPAGNLATG
VGPEDVACVMFTSGSTGRPKGVMSPHRALTGTYLGQDYAGFGPDEVFLQC
SPVSWDAFGLELFGALLFGARCVLQSGQNPDPLEIGELVARHGVTMLQLS
ASLFNFLVDEVPEAFEGVRYAITGGEPASVPHVAKARRDHPALRLGNGYG
PAESMGFTTHHAVVAGDLSGTALPIGVPLAGKRAYVLDDDLKPAANGALG
ELYVAGAGLAHGYVSRPALTAERFVADPFAGPGGERMYRTGDLARRRADG
VLEYVGR
3D structure
PDB4gr5 Structural Basis of the Interaction of MbtH-like Proteins, Putative Regulators of Nonribosomal Peptide Biosynthesis, with Adenylating Enzymes.
ChainC
Resolution1.92 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) T219 T239 A359 E360
Catalytic site (residue number reindexed from 1) T212 T232 A352 E353
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 APC C K227 W262 G332 E333 P334 N354 G355 Y356 P358 D449 R464 K220 W255 G325 E326 P327 N347 G348 Y349 P351 D442 R457
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008168 methyltransferase activity
GO:0031177 phosphopantetheine binding
Biological Process
GO:0043041 amino acid activation for nonribosomal peptide biosynthetic process
GO:0044550 secondary metabolite biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4gr5, PDBe:4gr5, PDBj:4gr5
PDBsum4gr5
PubMed23192349
UniProtD1GLU5

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