Structure of PDB 4ftb Chain C

Receptor sequence
>4ftbC (length=309) Species: 12287 (Flock House virus) [Search protein sequence]
ALTRLSQPGLAFLKCAFAPPDFNTDPGKGIPDRFEGKVVSRKDVLNQSIS
FTAGQDTFILIAPTPGVAYWSASVPAGTFPTSATTFNPVNYPGFTSMFGT
TSTSRSDQVSSFRYASMNVGIYPTSNLMQFAGSITVWKCPVKLSTVQFPV
ATDPATSSLVHTLVGLDGVLAVGPDNFSESFIKGVFSQSACNEPDFEFND
ILEGIQTLPPANVSLGSTGQPFTMDSGAEATSGVVGWGNMDTIVIRVSAP
EGAVNSAILKAWSCIEYRPNPNAMLYQFGHDSPPLDEVALQEYRTVARSL
PVAVIAAQN
3D structure
PDB4ftb Structural study of virus assembly intermediates reveals maturation event sequence and a staging position for externalized lytic peptides
ChainC
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.23.44: nodavirus endopeptidase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide C L56 K68 A72 D75 F76 E346 V350 L354 Q362 N363 L2 K14 A18 D21 F22 E292 V296 L300 Q308 N309
BS02 rna C Q61 L64 K68 Q7 L10 K14
BS03 CA C D221 G273 D167 G219
BS04 CA C D249 E251 D195 E197
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:4ftb, PDBe:4ftb, PDBj:4ftb
PDBsum4ftb
PubMed
UniProtP12870|CAPSD_FHV Capsid protein alpha (Gene Name=alpha)

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