Structure of PDB 4fnt Chain C

Receptor sequence
>4fntC (length=718) Species: 1422 (Geobacillus stearothermophilus) [Search protein sequence]
KQFHLRAGKASYVMQLFRSGYLAHVYWGKAVRDVRGARAFPRLDRAFSPN
PDPSDRTFSLDTLLQEYPAYGNTDFRAPAYQVQLENGSTVTDLRYKTHRI
YKGKPRLNGLPATYVEHEQEAETLEIVLGDALIGLEVTLQYTAYEKWNVI
TRSARFENKGGERLKLLRALSMSVDFPTADYDWIHLPGAWGRERWIERRP
LVTGVQAAESRRGASSHQQNPFIALVAKNADEHQGEVYGFSFVYSGNFLA
QIEVDQFGTARVSMGINPFDFTWLLQPGESFQTPEVVMVYSDQGLNGMSQ
TYHELYRTRLARGAFRDRERPILINNWEATYFDFNEEKIVNIARTEAELG
IELVVLDDGWFGERDDDRRSLGDWIVNRRKLPNGLDGLAKQVNELGLQFG
LWVEPEMVSPNSELYRKHPDWCLHVPNRPRSEGRNQLVLDYSREDVCDYI
IETISNVLASAPITYVKWDMNRHMTEIGSSALPPERQRETAHRYMLGLYR
VMDEITSRFPHILFESCSGGGGRFDPGMLYYMPQTWTSNNTDAVSRLKIQ
YGTSLVYPISAMGAHVSAVPNHQVGRVASLKTRGHVAMSGNFGYELDITK
LTETEKQMMKQQVAFYKDVRRLVQFGTFYRLLSPFEGNEAAWMFVSADRS
EALVAYFRVLAEANAPLSYLRLKGLDSNQDYEIEGLGVYGGDELVYAGVA
LPYRSSDFISMMWRLKAV
3D structure
PDB4fnt The molecular mechanism of the thermostable alpha-galactosidases AgaA and AgaB explained by X-ray crystallography and mutational studies
ChainC
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.22: alpha-galactosidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FRU C D53 R65 D44 R56
BS02 GLC C N480 N548 N471 N539
BS03 GLA C W336 D366 D367 W411 R443 K476 D478 N480 C526 G528 N548 W327 D357 D358 W402 R434 K467 D469 N471 C517 G519 N539
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004557 alpha-galactosidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0016052 carbohydrate catabolic process
GO:0033531 stachyose metabolic process
GO:0034484 raffinose catabolic process
GO:0051289 protein homotetramerization

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Molecular Function
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Biological Process
External links
PDB RCSB:4fnt, PDBe:4fnt, PDBj:4fnt
PDBsum4fnt
PubMed23012371
UniProtQ9ALJ4|AGAA_GEOSE Alpha-galactosidase AgaA (Gene Name=agaA)

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