Structure of PDB 4e5g Chain C

Receptor sequence
>4e5gC (length=181) Species: 284218 (Influenza A virus (A/Viet Nam/1203/2004(H5N1))) [Search protein sequence]
MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSD
GGSKHRFEIIEGRDRTMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIE
IGVTRREVHTYYLEKANKIKSEETHIHIFSFTGEEMATKADYTLDEESRA
RIKTRLFTIRQEMASRGLWDSFRQSERAAAE
3D structure
PDB4e5g Structural and Biochemical Basis for Development of Influenza Virus Inhibitors Targeting the PA Endonuclease.
ChainC
Resolution2.647 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MN C H41 D108 E119 I120 H41 D89 E100 I101
BS02 MN C E80 D108 E61 D89
BS03 XI7 C Y24 H41 E80 E119 K134 Y24 H41 E61 E100 K115
BS04 XI7 C Y24 E26 K34 I38 H41 Y24 E26 K34 I38 H41
Gene Ontology
Biological Process
GO:0039694 viral RNA genome replication

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Molecular Function

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Biological Process
External links
PDB RCSB:4e5g, PDBe:4e5g, PDBj:4e5g
PDBsum4e5g
PubMed22876176
UniProtQ5EP34

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