Structure of PDB 4dkp Chain C

Receptor sequence
>4dkpC (length=339) Species: 11686 (Human immunodeficiency virus type 1 (BRU ISOLATE)) [Search protein sequence]
VWKDADTTLFCASDAKAHETEVHNVWATHACVPTDPNPQEIHLENVTENF
NMWKNNMVEQMQEDVISLWDQSLQPCVKLTGGSVIKQACPKISFDPIPIH
YCTPAGYVILKCNDKNFNGTGPCKNVSSVQCTHGIKPVVSTQLLLNGSLA
EEEIIIRSENLTNNAKTIIVHLNKSVEINCTRPSNGDIRKAYCEINGTKW
NKVLKQVTEKLKEHFNNKTIIFQPPSGGDLEITMHSFNCRGEFFYCNTTQ
LFNNTCINGTITLPCKIKQIINMWQGTGQAMYAPPIDGKINCVSNITGIL
LTRDGGANNTSNETFRPGGGNIKDNWRSELYKYKVVQIE
3D structure
PDB4dkp Structure-Based Design, Synthesis, and Characterization of Dual Hotspot Small-Molecule HIV-1 Entry Inhibitors.
ChainC
Resolution1.7978 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 0LL C V255 E370 S375 F376 F382 N425 W427 G473 V139 E231 S236 F237 F243 N272 W274 G320 MOAD: Kd=1.9uM
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:4dkp, PDBe:4dkp, PDBj:4dkp
PDBsum4dkp
PubMed22497421
UniProtQ0ED31

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