Structure of PDB 4byf Chain C

Receptor sequence
>4byfC (length=696) Species: 9606 (Homo sapiens) [Search protein sequence]
RVGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQ
IYSRQHMERYRGVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGA
GKTEATKRLLQFYAETCPAPERGGAVRDRLLQSNPVLEAFGNAKTLRNDN
SSRFGKYMDVQFDFKGAPVGGHILSYLLEKSRVVHQNHGERNFHIFYQLL
EGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKVVRKALTVI
DFTEDEVEDLLSIVASVLHLGNIHFAANENAQVTTENQLKYLTRLLSVEG
STLREALTHRKIELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSL
ASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIE
LTLKSEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRP
GEATDLTFLEKLEDTVKHHPHFLTHKLADRKSLGRGEFRLLHYAGEVTYS
VTGFLDKNNDLLFRNLKETMCSSKNPIMSQCFDRSKRPETVATQFKMSLL
QLVEILQSKEPAYVRCIKPNDAKQPGRFDEVLIRHQVKYLGLLENLRVRR
AGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVAVLVRHLGYKPEEYK
MGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFL
3D structure
PDB4byf Crystal Structure of Human Myosin 1C-the Motor in Glut4 Exocytosis: Implications for Ca(2+) Regulation and 14-3-3 Binding.
ChainC
Resolution2.74 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S107 G108 T112 N157 S160 S161 G389 E391
Catalytic site (residue number reindexed from 1) S98 G99 T103 N148 S151 S152 G373 E375
Enzyme Commision number 3.6.4.1: Transferred entry: 5.6.1.8.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG C T112 S161 T103 S152
BS02 AOV C N53 S107 G108 G110 K111 T112 E113 N157 S160 S161 Y388 G389 N44 S98 G99 G101 K102 T103 E104 N148 S151 S152 Y372 G373
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
Cellular Component
GO:0016459 myosin complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:4byf, PDBe:4byf, PDBj:4byf
PDBsum4byf
PubMed24636949
UniProtO00159|MYO1C_HUMAN Unconventional myosin-Ic (Gene Name=MYO1C)

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