Structure of PDB 4bl9 Chain C

Receptor sequence
>4bl9C (length=724) Species: 9606,83333 [Search protein sequence]
TEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVA
ATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNG
KLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNL
QEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKN
KHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFK
GQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGA
VALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAA
SGRQTVDAALAAAQTNAAAPGLHAIYGECRRLYPDQPNPLQVTAIVKYWL
GGPDPLDYVSMYRNVGSPSANIPEHWHYISFGLSDLYGDNRVHEFTGTDG
PSGFGFELTFRLKRETGESAPPTWPAELMQGLARYVFQSENTFCSGDHVS
WHSPLDNSESRIQHMLLTEDPQMQPVQTPFGVVTFLQIVGVCTEELHSAQ
QWNGQGILELLRTVPIAGGPWLITDMRRGETIFEIDPHLQERVDKGIETD
GSNLSGVSAKCAWDDIRTRQLESVHLKFNQESGALIPLCLRGRLLHGRHF
TYKSITGDMAITFVSTGVEGAFATEEHPYAAHGPWLQILLTEEFVEKMLE
DLEKLPKEYSWPEKKLKVSILPDV
3D structure
PDB4bl9 Structural Basis of Sufu-GLI Interaction in Hedgehog Signalling Regulation
ChainC
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLC C D15 K16 E112 D13 K14 E110
BS02 GLC C W63 D66 R67 E154 P155 Y156 W341 W61 D64 R65 E152 P153 Y154 W339
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0015144 carbohydrate transmembrane transporter activity
GO:1901982 maltose binding
Biological Process
GO:0006974 DNA damage response
GO:0008643 carbohydrate transport
GO:0015768 maltose transport
GO:0034219 carbohydrate transmembrane transport
GO:0034289 detection of maltose stimulus
GO:0042956 maltodextrin transmembrane transport
GO:0055085 transmembrane transport
GO:0060326 cell chemotaxis
Cellular Component
GO:0016020 membrane
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space
GO:0043190 ATP-binding cassette (ABC) transporter complex
GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
GO:1990060 maltose transport complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4bl9, PDBe:4bl9, PDBj:4bl9
PDBsum4bl9
PubMed24311597
UniProtP0AEX9|MALE_ECOLI Maltose/maltodextrin-binding periplasmic protein (Gene Name=malE);
Q9UMX1|SUFU_HUMAN Suppressor of fused homolog (Gene Name=SUFU)

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