Structure of PDB 4bdo Chain C

Receptor sequence
>4bdoC (length=246) Species: 10116 (Rattus norvegicus) [Search protein sequence]
SLIVTTILEEPYVLFKKSLYGNDRFEGYCIDLLRELSTILGFTYEIRLVE
DGKYGAQDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSAPFM
TLGISILYRKGTPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDK
MWAFMSSRRQSVLVKSNEEGIQRVLTSDYAFLMESTTIEFVTQRNCNLTQ
IGGLIDSKGYGVGTPMGSPYRDKIGIAILQLQEEGKLHMMKEKWWR
3D structure
PDB4bdo Correlating Efficacy and Desensitization with Gluk2 Ligand-Binding Domain Movements.
ChainC
Resolution2.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 KAI C E440 Y488 P516 L517 A518 R523 G688 A689 T690 E738 E9 Y54 P82 L83 A84 R89 G134 A135 T136 E184 BindingDB: Ki=12.7nM,Kd=39nM,EC50=1800nM
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:4bdo, PDBe:4bdo, PDBj:4bdo
PDBsum4bdo
PubMed23720540
UniProtP42260|GRIK2_RAT Glutamate receptor ionotropic, kainate 2 (Gene Name=Grik2)

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