Structure of PDB 4b86 Chain C

Receptor sequence
>4b86C (length=115) Species: 9606 (Homo sapiens) [Search protein sequence]
MNPVNATALYISASRLVLNYDPGDPKAFTEINRLLPYFRQSLSCCVCGHL
LQDPIAPTNSTCQHYVCKTCKGKKMMMKPSCSWCKDYEQFEENKQLSILV
NCYKKLCEYITQTTL
3D structure
PDB4b86 Msl1-Mediated Dimerization of the Dosage Compensation Complex is Essential for Male X-Chromosome Regulation in Drosophila.
ChainC
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN C C44 C47 C67 C44 C47 C67
BS02 ZN C C62 H64 C81 C84 C62 H64 C81 C84
Gene Ontology
Molecular Function
GO:0061630 ubiquitin protein ligase activity
Cellular Component
GO:0072487 MSL complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:4b86, PDBe:4b86, PDBj:4b86
PDBsum4b86
PubMed23084835
UniProtQ9HCI7|MSL2_HUMAN E3 ubiquitin-protein ligase MSL2 (Gene Name=MSL2)

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