Structure of PDB 4b40 Chain C

Receptor sequence
>4b40C (length=672) Species: 85995 (Mycothermus thermophilus) [Search protein sequence]
SPLAAYEVDDSTGYLTSDVGGPIQDQTSLKAGIRGPTLLEDFMFRQKIQH
FDHERVPERAVHARGAGAHGTFTSYADWSNITAASFLNATGKQTPVFVRF
STAAGSRGSADTARDVHGFATRFYTDEGNFDIVGNNIPVFFIQDAIQFPD
LIHSVKPRPDNEIPQAATAHDSAWDFFSQQPSTMHTLFWAMSGHGIPRSY
RHMDGFGVHTFRFVKDDGSSKLIKWHFKSRQGKASLVWEEAQVLSGKNAD
FHRQDLWDAIESGNGPEWDVCVQIVDESQAQAFGFDLLDPTKIIPEEYAP
LTKLGLLKLDRNPTNYFAETEQVMFQPGHIVRGIDFTEDPLLQGRLFSYL
DTQLNRNGGPNFEQLPINMPRVPIHNNNRDGAGQMFIHRNKYPYTPNTLN
SGYPRQANQNAGRGFFTAPGRTASGALVREVSPTFNDHWSQPRLFFNSLT
PVEQQFLVNAMRFEISLVKSEEVKKNVLTQLNRVSHDVAVRVAAAIGLGA
PDADDTYYHNNKTAGVSIVGSGPLPTIKTLRVGILATTSESSALDQAAQL
RTRLEKDGLVVTVVAETLREGVDQTYSTADATGFDGVVVVDGAAALFASS
PLFPTGRPLQIFVDAYRWGKPVGVCGSEVLDAADVPEDGDGVYSEESVDM
FVEEFEKGLATFRFTDRFALDS
3D structure
PDB4b40 Investigating the Active Centre of the Scytalidium Thermophilum Catalase
ChainC
Resolution1.93 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H82 N155 Q346
Catalytic site (residue number reindexed from 1) H62 N135 Q326
Enzyme Commision number 1.11.1.6: catalase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HDD C R79 V81 H82 R119 V153 G154 N155 F160 F168 V228 H229 F345 R365 S368 Y369 T372 R59 V61 H62 R99 V133 G134 N135 F140 F148 V208 H209 F325 R345 S348 Y349 T352
BS02 CA C R178 H190 D191 S192 R158 H170 D171 S172
Gene Ontology
Molecular Function
GO:0004096 catalase activity
GO:0004601 peroxidase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0006979 response to oxidative stress
GO:0042744 hydrogen peroxide catabolic process
GO:0098869 cellular oxidant detoxification
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4b40, PDBe:4b40, PDBj:4b40
PDBsum4b40
PubMed23545640
UniProtR4GRT8

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