Structure of PDB 4avl Chain C

Receptor sequence
>4avlC (length=191) Species: 11320 (Influenza A virus) [Search protein sequence]
GMAMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFM
YSDFHFIDERGESIIVELLKHRFEIIEGRDRIMAWTVVNSICNTTGVEKP
KFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIEKTHIHIFSFTGEEM
ATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSER
3D structure
PDB4avl Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase.
ChainC
Resolution1.87 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MN C H41 D108 E119 I120 H44 D105 E116 I117
BS02 MN C E80 D108 E77 D105
BS03 TMP C Y24 K34 I38 H41 D108 E119 K134 Y27 K37 I41 H44 D105 E116 K131
Gene Ontology
Biological Process
GO:0039694 viral RNA genome replication

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Molecular Function

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Biological Process
External links
PDB RCSB:4avl, PDBe:4avl, PDBj:4avl
PDBsum4avl
PubMed22876177
UniProtC3W5S0

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