Structure of PDB 4au2 Chain C

Receptor sequence
>4au2C (length=338) Species: 9615 (Canis lupus familiaris) [Search protein sequence]
MLSPKAATLAERSAGLAFSLYQAMAKDQAVENILLSPVVVASSLGLVSLG
GKATTASQAKAVLSLRDEEVHAGLGELLRSLSNSTARNVTWKLGSRLYSV
SFAEDFVRSSKQHYNCEHSALQSINEWAAQTTDGKLPEVTKDDGALLVNA
MFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVTMMHRTGLYNYYDDEKEKL
QIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQKKAVA
ISLPKGVVEVTHDLQKHLAGLGLTEAIDKDLSRMLASVFHATAFEWDTEG
NPELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRPK
3D structure
PDB4au2 Molecular Basis for the Action of the Collagen-Specific Chaperone Hsp47/Serpinh1 and its Structure-Specific Client Recognition.
ChainC
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C M218 R222 M225 H238 L381 D385 M165 R169 M172 H185 L309 D313
BS02 peptide C R228 L381 Y383 R175 L309 Y311
Gene Ontology
Molecular Function
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005518 collagen binding
Cellular Component
GO:0005581 collagen trimer
GO:0005615 extracellular space
GO:0005783 endoplasmic reticulum

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Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:4au2, PDBe:4au2, PDBj:4au2
PDBsum4au2
PubMed22847422
UniProtC7C419

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