Structure of PDB 4aq8 Chain C

Receptor sequence
>4aq8C (length=237) Species: 10090 (Mus musculus) [Search protein sequence]
QYDDDWQYEDCKLARGGPPATIVAIDEESRNGTILVDNMLIKGTAGGPDP
TIELSLKDNVDYWVLLDPVKQMLFLNSTGRVLDRDPPMNIHSIVVQVQCV
NKKVGTVIYHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFS
GDNGATDIDDGPNGQIEYVIQYNPEDPTSNDTFEIPLMLTGNVVLRKRLN
YEDKTRYYVIIQANDRAQNLNERRTTTTTLTVDLEHH
3D structure
PDB4aq8 Structure of a Force-Conveying Cadherin Bond Essential for Inner-Ear Mechanotransduction
ChainC
Resolution2.63 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA C N120 N122 D157 D159 N163 D215 N120 N122 D157 D159 N163 D215
BS02 CA C E27 E28 D83 D85 D121 E27 E28 D83 D85 D121
BS03 CA C E27 D85 D118 R119 D121 D159 E27 D85 D118 R119 D121 D159
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007605 sensory perception of sound
GO:0048839 inner ear development
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0032420 stereocilium

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4aq8, PDBe:4aq8, PDBj:4aq8
PDBsum4aq8
PubMed23135401
UniProtQ99PJ1|PCD15_MOUSE Protocadherin-15 (Gene Name=Pcdh15)

[Back to BioLiP]