Structure of PDB 4akb Chain C

Receptor sequence

>4akbC (length=133) Species: 3490 (Artocarpus integer)

GKAFDDGAFTGIREINLSYNKETAIGDFQVVYDLNGSPYVGENHKSFITG
FTPVKISLDFPSEYIMEVSGYTGKVSGYVVVRSLTFKTNKKTYGPYGVTS
GTPFSLPIENGLIVGFKGSIGYWLDYFSMYLSL

3D structure

• PDB: 4akb Structures and Binding Specificity of Galactose- and Mannose-Binding Lectins from Champedak: Differences from Jackfruit Lectins
• Chain: C
• Resolution: 1.95 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	C	T10 F60 P61 L112 L133	T10 F60 P61 L112 L133
BS02	peptide	C	T72 V79 F104 D125 Y126 F127 S128 M129 Y130 L131	T72 V79 F104 D125 Y126 F127 S128 M129 Y130 L131
BS03	peptide	C	S105 P107 I108 E109 N110 L133	S105 P107 I108 E109 N110 L133
BS04	GAL	C	G1 Y78 G121 Y122 W123 D125	G1 Y78 G121 Y122 W123 D125

Gene Ontology

Molecular Function

• GO:0019862 IgA binding
• GO:0030246 carbohydrate binding

Biological Process

• GO:0008150 biological_process

Cellular Component

• GO:0005575 cellular_component

External links

• PDB: RCSB:4akb, PDBe:4akb, PDBj:4akb
• PDBsum: 4akb
• PubMed: 24915077
• UniProt: P18670|LECA_ARTIN Agglutinin alpha chain