Structure of PDB 4a9j Chain C

Receptor sequence
>4a9jC (length=106) Species: 9606 (Homo sapiens) [Search protein sequence]
NQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTI
KRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQK
VASMPQ
3D structure
PDB4a9j Fragment-Based Discovery of Bromodomain Inhibitors Part 1: Inhibitor Binding Modes and Implications for Lead Discovery.
ChainC
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TYL C V103 L108 N156 I162 V27 L32 N80 I86
External links
PDB RCSB:4a9j, PDBe:4a9j, PDBj:4a9j
PDBsum4a9j
PubMed22136404
UniProtP25440|BRD2_HUMAN Bromodomain-containing protein 2 (Gene Name=BRD2)

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