Structure of PDB 4a5a Chain C

Receptor sequence
>4a5aC (length=592) Species: 5811 (Toxoplasma gondii) [Search protein sequence]
VDADTEKRINVGKKHLQTLRNLETRCHDSLQALVVIDAGSSSTRTNVFLA
KTRSCPNKGRSIDPDSIQLIGAGKRFAGLRVVLEEWLDTYAGKDWESRPV
DARLLFQYVPQMHEGAKKLMQLLEEDTVAILDSQLNEKQKVQVKALGIPV
MLCSTAGVRDFHEWYRDALFVLLRHLINNPSPAHGYKFFTNPFWTRPITG
AEEGLFAFITLNHLSRRLGEDPARSMIDEYGVKQSRNDLAGVVEVGGASA
QIVFPLQEGTVLPSSVRAVNLQRERLLPERYPSADVVSVSFMQLGMASSA
GLFLKELCSNDEFLQGGICSNPCLFKGFQQSCSAGEVEVRPDGSASVNED
VRKNRLKPLATYCSVNNPEISFKVTNEMQCRENSIDPTKPLAERMKIENC
SIIKGTGNFDKCVSQVESILVAPKLPLPANIEAASSGFESVDQVFRFASS
TAPMIVTGGGMLAAINTLKDHRLLRSDFSGDVEELAEAAREFCSSEVIIR
TDGPVIQLPGEQKLNSLNFDLCKTMALTVSLLRHMAAGENQPSFIKWEKS
IAGPDGKPLADLGWQVGVILHHVLFTEEWGRNAYEAGYSHNL
3D structure
PDB4a5a Structural Insight Into the Activation Mechanism of Toxoplasma Gondii Nucleoside Triphosphate Diphosphohydrolases by Disulfide Reduction.
ChainC
Resolution2.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.15: nucleoside-triphosphate phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP C G72 S73 S74 R77 R108 T188 A189 G280 M329 A496 G39 S40 S41 R44 R75 T155 A156 G247 M296 A463
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0017111 ribonucleoside triphosphate phosphatase activity
Cellular Component
GO:0005576 extracellular region
GO:0020003 symbiont-containing vacuole

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Molecular Function
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Cellular Component
External links
PDB RCSB:4a5a, PDBe:4a5a, PDBj:4a5a
PDBsum4a5a
PubMed22130673
UniProtQ27893|NTP1_TOXGO Nucleoside-triphosphatase 1 (Gene Name=NTP3)

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