Structure of PDB 3ztd Chain C

Receptor sequence
>3ztdC (length=139) Species: 9606 (Homo sapiens) [Search protein sequence]
LRSVNSREPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRIHSY
RGHLWLFRDAGTHDGLLVNQTELFVPSDGQPIFANITLPVYTLKERCLQV
VRSLVKPENYRRLDIVRSLYEDLEDHPNVQKDLERLTQE
3D structure
PDB3ztd Dissecting Fragment-Based Lead Discovery at the Von Hippel-Lindau Protein:Hypoxia Inducible Factor 1Alpha Protein-Protein Interface.
ChainC
Resolution2.79 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZTD C W88 Y98 P99 I109 H110 S111 Y112 H115 W117 W26 Y36 P37 I47 H48 S49 Y50 H53 W55 PDBbind-CN: -logKd/Ki=4.02,Kd=96.2uM
External links
PDB RCSB:3ztd, PDBe:3ztd, PDBj:3ztd
PDBsum3ztd
PubMed23102223
UniProtP40337|VHL_HUMAN von Hippel-Lindau disease tumor suppressor (Gene Name=VHL)

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