Structure of PDB 3ztc Chain C

Receptor sequence
>3ztcC (length=141) Species: 9606 (Homo sapiens) [Search protein sequence]
LRSVNSREPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRIHSY
RGHLWLFRDAGTHDGLLVNQTELFVPSLNDGQPIFANITLPVYTLKERCL
QVVRSLVKPENYRRLDIVRSLYEDLEDHPNVQKDLERLTQE
3D structure
PDB3ztc Dissecting Fragment-Based Lead Discovery at the Von Hippel-Lindau Protein:Hypoxia Inducible Factor 1Alpha Protein-Protein Interface.
ChainC
Resolution2.65 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TR0 C W88 Y98 P99 I109 H110 S111 Y112 H115 W117 W26 Y36 P37 I47 H48 S49 Y50 H53 W55 PDBbind-CN: -logKd/Ki=4.56,Kd=27.7uM
External links
PDB RCSB:3ztc, PDBe:3ztc, PDBj:3ztc
PDBsum3ztc
PubMed23102223
UniProtP40337|VHL_HUMAN von Hippel-Lindau disease tumor suppressor (Gene Name=VHL)

[Back to BioLiP]