Structure of PDB 3znr Chain C

Receptor sequence
>3znrC (length=359) Species: 9606 (Homo sapiens) [Search protein sequence]
TTGLIYDSVMLKHQCSCGDNSRHPEHAGRIQSIWSRLQERGLRSQCECLR
GRKASLEELQSVHSERHVLLYGTNPLPCGGVGVDTDTIWNELHSSNAARW
AAGSVTDLAFKVASRELKNGFAVVRPPGHHADHSTAMGFCFFNSVAIACR
QLQQQSKASKILIVDWDVHHGNGTQQTFYQDPSVLYISLHRHDDGNFFPG
SGAVDEVGAGSGEGFNVNVAWAGGLDPPMGDPEYLAAFRIVVMPIAREFS
PDLVLVSAGFDAAEGHPAPLGGYHVSAKCFGYMTQQLMNLAGGAVVLALE
GGHDLTAICDASEACVAALLGNRVDPLSEEGWKQKPNLNAIRSLEAVIRV
HSKYWGCMQ
3D structure
PDB3znr Selective Class Iia Histone Deacetylase Inhibition Via a Non-Chelating Zinc Binding Group
ChainC
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.1.-
3.5.1.98: histone deacetylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN C D707 H709 D801 D167 H169 D261
BS02 ZN C C533 C535 H541 C618 C15 C17 H23 C78
External links
PDB RCSB:3znr, PDBe:3znr, PDBj:3znr
PDBsum3znr
PubMed23524983
UniProtQ8WUI4|HDAC7_HUMAN Histone deacetylase 7 (Gene Name=HDAC7)

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