Structure of PDB 3x1j Chain C

Receptor sequence
>3x1jC (length=158) Species: 350703 (Pseudomonas aeruginosa 2192) [Search protein sequence]
MNRVLYPGTFDPITKGHGDLIERASRLFDHVIIAVAASPKKNPLFSLEQR
VALAQEVTKHLPNVEVVGFSTLLAHFVKEQKANVFLRGLRAVSDFEYEFQ
LANMNRQLAPDVESMFLTPSEKYSFISSTLVREIAALGGDISKFVHPAVA
DALAERFK
3D structure
PDB3x1j Transition of phosphopantetheine adenylyltransferase from catalytic to allosteric state is characterized by ternary complex formation in Pseudomonas aeruginosa
ChainC
Resolution2.334 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H17 K41 R90 S128
Catalytic site (residue number reindexed from 1) H17 K41 R90 S128
Enzyme Commision number 2.7.7.3: pantetheine-phosphate adenylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ACO C L130 E133 I134 L137 L130 E133 I134 L137 MOAD: Ki=8.4uM
BS02 ACO C Y6 P7 G8 T9 H17 K41 F69 L73 R87 R90 Y97 L101 N105 S127 S128 T129 Y6 P7 G8 T9 H17 K41 F69 L73 R87 R90 Y97 L101 N105 S127 S128 T129 MOAD: Ki=8.4uM
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004595 pantetheine-phosphate adenylyltransferase activity
GO:0005524 ATP binding
GO:0008771 [citrate (pro-3S)-lyase] ligase activity
GO:0016779 nucleotidyltransferase activity
Biological Process
GO:0009058 biosynthetic process
GO:0015937 coenzyme A biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:3x1j, PDBe:3x1j, PDBj:3x1j
PDBsum3x1j
PubMed27041211
UniProtA0A0X1KGP2

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