Structure of PDB 3wx9 Chain C

Receptor sequence

>3wx9C (length=404) Species: 70601 (Pyrococcus horikoshii OT3) [Search protein sequence]

SMLGDVERFFSKKALEMRASEVRELLKLVETSDIISLAGGLPNPKTFPKE
IIRDILVEIMEKYADKALQYGTTKGFTPLRETLMKWLGKRYGISQDNDIM
ITSGSQQALDLIGRVFLNPGDIVVVEAPTYLAALQAFNFYEPQYIQIPLD
DEGMKVEILEEKLKELKSQGKKVKVVYTVPTFQNPAGVTMNEDRRKYLLE
LASEYDFIVVEDDPYGELRYSGNPEKKIKALDNEGRVIYLGTFSKILAPG
FRIGWMVGDPGIIRKMEIAKQSTDLCTNVFGQVVAWRYVDGGYLEKHIPE
IRKFYKPRRDAMLEALEEFMPEGVKWTKPEGGMFIWVTLPDGIDSKKMLE
RAIKKGVAYVPGEAFYAHRDVKNTMRLNFTYVDEDKIMEGIKRLAETIKE
ELKA

3D structure

PDB

3wx9 Crystal structure of Pyrococcus horikoshii kynurenine aminotransferase in complex with PMP, GLA, 4AD, 2OG, GLU and KYA

Chain

Resolution

1.58 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	PMP	C	G128 S129 Q130 Y154 N208 D236 P238 Y239 T266 S268 K269 R276	G104 S105 Q106 Y130 N184 D212 P214 Y215 T242 S244 K245 R252
BS02	AKG	C	Y115 D237 G240 E241 K251 Y263 G265 T266 W279	Y91 D213 G216 E217 K227 Y239 G241 T242 W255
BS03	G9A	C	G64 Y154 N208 R400	G40 Y130 N184 R376
BS04	3EE	C	G63 G64 L65	G39 G40 L41
BS05	KYA	C	S44 V46 L155 Q159 K370 A388 R393	S20 V22 L131 Q135 K346 A364 R369

Gene Ontology

	Molecular Function
GO:0008483	transaminase activity
GO:0030170	pyridoxal phosphate binding

	Biological Process
GO:0009058	biosynthetic process
GO:1901605	alpha-amino acid metabolic process

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Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:3wx9, PDBe:3wx9, PDBj:3wx9
PDBsum	3wx9
PubMed
UniProt	O57946

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