Structure of PDB 3wgi Chain C

Receptor sequence
>3wgiC (length=217) Species: 509192 (Thermoanaerobacter ethanolicus JW 200) [Search protein sequence]
KTIVSMAVIRRLPRYHRYLEELLKNDVKRISSRELSEKMGVTASQIRQDL
NNFGGFGQQGYGYNVEELYNNLTKILGLDKTYNTIIIGAGNLGQAIANYT
SFEKSGFNLKGIFDINPRLFGLKIRDVEVMDVETVEDFIARNKIDIGILC
IPKDNAQYTADRLVRAGIKAIWNFLPIDLKVPDDVILENVHLSDSLFTVS
YRLNEEELFKKLKGETA
3D structure
PDB3wgi Distinct structural features of Rex-family repressors to sense redox levels in anaerobes and aerobes.
ChainC
Resolution3.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna C S34 S35 R50 N54 G58 G60 Q62 G63 G65 Y66 S31 S32 R47 N51 G55 G57 Q59 G60 G62 Y63
BS02 dna C S8 R14 T45 S47 Q48 Q51 Q62 S5 R11 T42 S44 Q45 Q48 Q59
BS03 NAJ C G91 G93 N94 L95 D117 I118 C153 I154 P155 F177 L195 S196 G88 G90 N91 L92 D114 I115 C150 I151 P152 F174 L192 S193
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0045892 negative regulation of DNA-templated transcription
GO:0051775 response to redox state
Cellular Component
GO:0005737 cytoplasm

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:3wgi, PDBe:3wgi, PDBj:3wgi
PDBsum3wgi
PubMed25463021
UniProtD5KM69

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