Structure of PDB 3vsv Chain C

Receptor sequence

>3vsvC (length=638)

MEYHVAKTGSDEGKGTLKDPFLTINKAASVAMAGDTIIVHEGVYREWVKP
KYKGLSDKRRITYKAAEGEKVVIKGSERIQSWQRVEGNVWRCQLPNSFFG
EFNPYKEEVFGDWLLTVNEKKHLGDVYLNGMSFYEVTNYEDLFNPQLRTE
VLDHWTQKIVPIKNAEQTKYVWYAEVDREKTTIYANFQGADPNEEFVEIN
VRRSCFYPVETGIDYITVKGFEMAHAATPWAPPTADQPGLIGPNWSKGWI
IEDNIIHDAKCSAISIGKEATTGNNYRSIRKDKPGYQYQLEAVFNAKRNG
WSKEKIGSHIIRNNTIYDCGQNAIVGHLGGVFSEIYNNHIYNIALKREFY
GHEIAGIKLHAAIDVQIHHNRIHDCSLGLWLDWEAQGTRVSKNLFYNNNR
DVFVEVSHGPYLVDHNILSSEYAIDNMSQGGAYINNLIAGKMNQRKVLNR
STQYHLPHSTEVAGFAFVYGGDDRFYNNIFIGKEGLENVGTSHYNNCTTS
LEEYIEKVNEVPGDLGEFERVEQPVYINKNAYFNGAEPFEKEKDNLVKKD
FDPKLAIIDEGDEVYLSLQLPDEFENIVGDIHSTKTLERVRIVDAEYESP
DGKELVLDTDYLDAKKPENSSIGPIALLKKGNNYIKVW

3D structure

• PDB: 3vsv The substrate/product-binding modes of a novel GH120 beta-xylosidase (XylC) from Thermoanaerobacterium saccharolyticum JW/SL-YS485
• Chain: C
• Resolution: 1.48 Å

Enzymatic activity

• Enzyme Commision number: 3.2.1.37: xylan 1,4-beta-xylosidase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	XYP	C	W113 P233 Q289 H352 E353 K358 H360 D382 W383 E405 R450	W113 P233 Q289 H352 E353 K358 H360 D382 W383 E405 R450
BS02	XYP	C	Y341 H373	Y341 H373
BS03	XYP	C	D57 R312	D57 R312
BS04	XYP	C	Q366 H368 R389 S391 K392	Q366 H368 R389 S391 K392
BS05	XYP	C	V136 P145 Q146 R148 T168	V136 P145 Q146 R148 T168
BS06	XYS	C	N397 N398 N399 E421	N397 N398 N399 E421
BS07	XYS	C	P161 R347 D374 N399	P161 R347 D374 N399
BS08	XYS	C	K585 E604	K585 E604
BS09	XYP	C	T211 N299	T211 N299

Gene Ontology

Molecular Function

• GO:0016837 carbon-oxygen lyase activity, acting on polysaccharides

Cellular Component

• GO:0005576 extracellular region

External links

• PDB: RCSB:3vsv, PDBe:3vsv, PDBj:3vsv
• PDBsum: 3vsv
• PubMed: 22992047
• UniProt: A2ICH1