Structure of PDB 3vqx Chain C

Receptor sequence
>3vqxC (length=254) Species: 2209 (Methanosarcina mazei) [Search protein sequence]
LTKSQTDRLEVLLNPKDESGKPFRELESELLSRRKKDLQQIYAEERENYL
GKLEREITRFFVDRGFLEIKSPILIPLEYIERMGIDNDLSKQIFRVDKNF
CLRPMLAPNLYNYLRKLDRALPDPIKIFEIGPCYRKGKEHLEEFTMLNFC
QMGSGCTRENLESIITDFLNHLGIDFKIVGCMVYGDTLDVMHGDLELSSA
VVGPIPLDREWGIDKPWIGAGFGLERLLKVKHDFKNIKRAARSGSYYNGI
STNL
3D structure
PDB3vqx A novel crystal form of pyrrolysyl-tRNA synthetase reveals the pre- and post-aminoacyl-tRNA synthesis conformational states of the adenylate and aminoacyl moieties and an asparagine residue in the catalytic site
ChainC
Resolution2.3 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 6.1.1.26: pyrrolysine--tRNA(Pyl) ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BLK C A302 Y306 R330 H338 L339 F342 E396 S399 W417 G423 R426 A107 Y111 R135 H140 L141 F144 E196 S199 W217 G223 R226
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0043039 tRNA aminoacylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3vqx, PDBe:3vqx, PDBj:3vqx
PDBsum3vqx
PubMed23275158
UniProtQ8PWY1|PYLS_METMA Pyrrolysine--tRNA ligase (Gene Name=pylS)

[Back to BioLiP]