Structure of PDB 3vff Chain C

Receptor sequence
>3vffC (length=256) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
DLADRFAELERRYDARLGVYVPATGTTAAIEYRADERFAFCSTFKAPLVA
AVLHQNPLTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYS
DGTAANLLLADLGGPGGGTAAFTGYLRSLGDTVSRLDPPGDERDTTTPHA
IALVLQQLVLGNALPPDKRALLTDWMARNTTGAKRIRAGFPADWKVIDKT
GTGDYGRANDIAVVWSPTGVPYVVAVMSDRAGGGYDAEPREALLAEAATC
VAGVLA
3D structure
PDB3vff BlaC-Specific Fluorogenic Probes for Rapid Tuberculosis Detection
ChainC
Resolution2.777 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S70 K73 S130 K234 T237
Catalytic site (residue number reindexed from 1) S42 K45 S100 K199 T202
Enzyme Commision number 3.5.2.6: beta-lactamase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CD8 C C69 S70 S130 T235 G236 T237 C41 S42 S100 T200 G201 T202
Gene Ontology
Molecular Function
GO:0008800 beta-lactamase activity
GO:0016787 hydrolase activity
Biological Process
GO:0017001 antibiotic catabolic process
GO:0030655 beta-lactam antibiotic catabolic process
GO:0046677 response to antibiotic
Cellular Component
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0042597 periplasmic space

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3vff, PDBe:3vff, PDBj:3vff
PDBsum3vff
PubMed
UniProtP9WKD3|BLAC_MYCTU Beta-lactamase (Gene Name=blaC)

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