Structure of PDB 3vcy Chain C

Receptor sequence
>3vcyC (length=419) Species: 388396 (Aliivibrio fischeri MJ11) [Search protein sequence]
MDKFRIQGSDKPLSGEVTISGAKNAALPILFASLLAEEPVEVANVPKLRD
VDTTMELLKRLGAEVSRNGSVHIDASGVNDFCAPYDLVKTMRASIWALGP
LVARFGKGQVSLPGGCAIGARPVDLHIHGLEQLGATIKLEEGYVKAEVDG
RLKGAHIVMDKVSVGATITVMCAATLAEGTTVLENAAREPEIVDTANFLN
AIGAKVSGMGTDTITIEGVERLGGGYHEVVADRIETGTFLVAAAVSGGKI
VCKNTKAHLLEAVLAKLEEAGADVQTGDDWISLDMTGRELKAVNIRTAPH
PAFPTDMQAQFTLLNMMAKGSGIITETIFENRFMHIPELQRMGAHAEIEG
NTAICGDTDGLSGAQVMATDLRASASLVIAGCIAKGETIVDRIYHIDRGY
DKIEDKLTALGANIERVHS
3D structure
PDB3vcy Structure of MurA (UDP-N-acetylglucosamine enolpyruvyl transferase) from Vibrio fischeri in complex with substrate UDP-N-acetylglucosamine and the drug fosfomycin.
ChainC
Resolution1.925 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) K23 N24 D50 A93 C116 R121 H300 D306 R398
Catalytic site (residue number reindexed from 1) K23 N24 D50 A93 C116 R121 H300 D306 R398
Enzyme Commision number 2.5.1.7: UDP-N-acetylglucosamine 1-carboxyvinyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UD1 C N24 W96 A120 R121 P122 V123 D124 L125 S163 V164 G165 T305 D306 I328 F329 N24 W96 A120 R121 P122 V123 D124 L125 S163 V164 G165 T305 D306 I328 F329
BS02 FFQ C R92 C116 R398 R92 C116 R398
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008760 UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
GO:0016740 transferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
Biological Process
GO:0008360 regulation of cell shape
GO:0009252 peptidoglycan biosynthetic process
GO:0019277 UDP-N-acetylgalactosamine biosynthetic process
GO:0051301 cell division
GO:0071555 cell wall organization
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3vcy, PDBe:3vcy, PDBj:3vcy
PDBsum3vcy
PubMed22505403
UniProtB5F9P4|MURA_ALIFM UDP-N-acetylglucosamine 1-carboxyvinyltransferase (Gene Name=murA)

[Back to BioLiP]