Structure of PDB 3v3o Chain C

Receptor sequence
>3v3oC (length=364) Species: 818 (Bacteroides thetaiotaomicron) [Search protein sequence]
SDKNVAIIGGGPVGLTMAKLLQQNGIDVSVYERDNDREARIFGGTLDLHK
GSGQEAMKKAGLLQTYYDLALPMGVNIADKKGNILSTKNVKPENRFDNPE
INRNDLRAILLNSLENDTVIWDRKLVMLEPGKKKWTLTFENKPSETADLV
ILANGGMSKVRKFVTDTEVEETGTFNIQADIHQPEINCPGFFQLCNGNRL
MASHQGNLLFANPNNNGALHFGISFKTPDEWKVDFQNRNSVVDFLLKKFS
DWDERYKELIHATLSFVGLATRIFPLEKPWKSKRPLPITMIGDAAHLMPP
FAGQGVNSGLVDALILSDNLADGKFNSIEEAVKNYEQQMFIYGKEAQEES
TQNEIEMFKPDFTF
3D structure
PDB3v3o Crystal structure of TetX2 T280A: an adaptive mutant in complex with tigecycline
ChainC
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.13.231: tetracycline 11a-monooxygenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 T1C C Q192 F224 P318 F319 G321 Q178 F210 P300 F301 G303
BS02 FAD C G23 G25 P26 V27 E46 R47 R117 K138 L139 N168 G169 Q192 G310 D311 P318 G323 V324 G9 G11 P12 V13 E32 R33 R103 K124 L125 N154 G155 Q178 G292 D293 P300 G305 V306
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004497 monooxygenase activity
GO:0071949 FAD binding
Biological Process
GO:0046677 response to antibiotic
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3v3o, PDBe:3v3o, PDBj:3v3o
PDBsum3v3o
PubMed
UniProtQ93L51|TETX_BACT4 Flavin-dependent monooxygenase (Gene Name=tetX2)

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