Structure of PDB 3u5k Chain C

Receptor sequence
>3u5kC (length=123) Species: 9606 (Homo sapiens) [Search protein sequence]
MNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKL
NLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKP
GDDIVLMAEALEKLFLQKINELP
3D structure
PDB3u5k Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family.
ChainC
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 08J C W81 P82 V87 L92 N140 I146 W39 P40 V45 L50 N98 I104
External links
PDB RCSB:3u5k, PDBe:3u5k, PDBj:3u5k
PDBsum3u5k
PubMed22137933
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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