Structure of PDB 3tnl Chain C

Receptor sequence
>3tnlC (length=289) Species: 169963 (Listeria monocytogenes EGD-e) [Search protein sequence]
NKITERITGHTELIGLIATPIRHSLSPTMHNEAFAKLGLDYVYLAFEVGD
KELKDVVQGFRAMNLRGWNVSMPNKTNIHKYLDKLSPAAELVGAVNTVVN
DDGVLTGHITDGTGYMRALKEAGHDIIGKKMTICGAGGAATAICIQAALD
GVKEISIFNRKDDFYANAEKTVEKINSKTDCKAQLFDIEDHEQLRKEIAE
SVIFTNATGVGMKPFEGETLLPSADMLRPELIVSDVVYKPTKTRLLEIAE
EQGCQTLNGLGMMLWQGAKAFEIWTHKEMPVDYIKEILF
3D structure
PDB3tnl 1.45 Angstrom Crystal Structure of Shikimate 5-dehydrogenase from Listeria monocytogenes in Complex with Shikimate and NAD.
ChainC
Resolution1.45 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.1.1.25: shikimate dehydrogenase (NADP(+)).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD C M74 G137 G139 G140 A141 N161 R162 D164 F166 T210 V212 M214 V238 Y240 M264 M265 M72 G135 G137 G138 A139 N159 R160 D162 F164 T208 V210 M212 V236 Y238 M262 M263
BS02 SKM C S26 S28 N71 K77 N98 D113 Q268 S24 S26 N69 K75 N96 D111 Q266
Gene Ontology
Molecular Function
GO:0004764 shikimate 3-dehydrogenase (NADP+) activity
GO:0016491 oxidoreductase activity
GO:0050661 NADP binding
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0009073 aromatic amino acid family biosynthetic process
GO:0009423 chorismate biosynthetic process
GO:0019632 shikimate metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3tnl, PDBe:3tnl, PDBj:3tnl
PDBsum3tnl
PubMed
UniProtQ8Y9N5|AROE_LISMO Shikimate dehydrogenase (NADP(+)) (Gene Name=aroE)

[Back to BioLiP]