Structure of PDB 3t6v Chain C

Receptor sequence

>3t6vC (length=495) Species: 92696 (Steccherinum ochraceum)

VQIGPVTDLHIVNADIVPDGFVRPAVNAGGTFPGPVIAGNVGDNFQIVTF
NQLIECSMLVDTSIHWHGEFQKGTNWADGPAFITQCPIIVGNSFSYNFNV
PGMAGTYWYHSHLTTQYCDGLRGPFVVYDPNDPDANLYDVDDDTTIITLA
DWYHVLAKEMGAGGAITADSTLIDGLGRTHVNVAAVPLSVITVEVGKRYR
MRLVSISCDPNYDFSIDGHDMTIIETDGVDSQELTVDEIQIFAAQRYSFV
LNANQPVGNYWIRANPNSGGEGFDGGINSAILRYDGATTADPVTVASTVH
TKCLIETDLHPLSRNGVPGNPHQGGADCNLNLSLGFACGNFVINGVSFTP
PTVPVLLQICSGANTAADLLPSGSVISLPSNSTIEIALPAGAAGGPHPFH
LHGHDFAVSESASNSTSNYDDPIWRDVVSIGGVGDNVTIRFCTDNPGPWF
LHCHIDWHLDAGFAIVFAEDIPNTASANPVPEAWSNLCPSYDSAH

3D structure

• PDB: 3t6v Reaction intermediates and redox state changes in a blue laccase from Steccherinum ochraceum observed by crystallographic high/low X-ray dose experiments.
• Chain: C
• Resolution: 2.0 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): H65 H67 H110 H112 H397 H400 H402 H452 C453 H454 I455 H458 F463
• Catalytic site (residue number reindexed from 1): H65 H67 H110 H112 H397 H400 H402 H452 C453 H454 I455 H458 F463
• Enzyme Commision number: 1.10.3.2: laccase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	CU	C	H397 C453 H458	H397 C453 H458
BS02	CU	C	H67 H110 H454	H67 H110 H454
BS03	CU	C	H112 H402 H452	H112 H402 H452
BS04	CU	C	H65 H400 H402	H65 H400 H402

Gene Ontology

Molecular Function

• GO:0005507 copper ion binding
• GO:0016491 oxidoreductase activity
• GO:0046872 metal ion binding
• GO:0052716 hydroquinone:oxygen oxidoreductase activity

Cellular Component

• GO:0005576 extracellular region

External links

• PDB: RCSB:3t6v, PDBe:3t6v, PDBj:3t6v
• PDBsum: 3t6v
• PubMed: 22341982
• UniProt: I1SB14