Structure of PDB 3scg Chain C

Receptor sequence
>3scgC (length=193) Species: 43759 (Streptomyces wedmorensis) [Search protein sequence]
TASTGFAELLKDRREQVKMDHAALASLLGETPETVAAWENGEGGELTLTQ
LGRIAHVLGTSIGALTPPAGNDLDDGVIIQMPDERPILKGVRDNVDYYVY
NCLVRTKRAPSLVPLVVDVLTDNPDDAKFNSGHAGNEFLFVLEGEIHMKW
GDKENPKEALLPTGASMFVEEHVPHAFTAAKGTGSAKLIAVNF
3D structure
PDB3scg Structural basis of regiospecificity of a mononuclear iron enzyme in antibiotic fosfomycin biosynthesis.
ChainC
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.11.1.23: (S)-2-hydroxypropylphosphonic acid epoxidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TB6 C R97 Y103 Y105 N135 H138 E142 H180 F182 R92 Y98 Y100 N130 H133 E137 H175 F177
BS02 FE2 C H138 E142 H180 H133 E137 H175
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0008198 ferrous iron binding
GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity
Biological Process
GO:0017000 antibiotic biosynthetic process
GO:0051289 protein homotetramerization
GO:1901766 phosphinothricin biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3scg, PDBe:3scg, PDBj:3scg
PDBsum3scg
PubMed21682308
UniProtQ56185|HPPE_STRWE (S)-2-hydroxypropylphosphonic acid epoxidase (Gene Name=hppE)

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