Structure of PDB 3rwb Chain C

Receptor sequence
>3rwbC (length=247) Species: 381 (Mesorhizobium loti) [Search protein sequence]
TERLAGKTALVTGAAQGIGKAIAARLAADGATVIVSDINAEGAKAAAASI
GKKARAIAADISDPGSVKALFAEIQALTGGIDILVNNASIVPFVAWDDVD
LDHWRKIIDVNLTGTFIVTRAGTDQMRAAGKAGRVISIASNTFFAGTPNM
AAYVAAKGGVIGFTRALATELGKYNITANAVTPGLIESDGVKASPHNEAF
GFVEMLQAMKGKGQPEHIADVVSFLASDDARWITGQTLNVDAGMVRH
3D structure
PDB3rwb Crystal structure of complex of 4PAL (4-Pyridoxolactone) and PLDH (tetrameric pyridoxal 4-dehydrogenase) from Mesorhizobium loti
ChainC
Resolution1.699 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) G18 S141 Y154 K158
Catalytic site (residue number reindexed from 1) G17 S140 Y153 K157
Enzyme Commision number 1.1.1.107: pyridoxal 4-dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD C G14 Q17 G18 I19 D38 I39 D61 I62 N88 A89 S90 I139 Y154 K158 P184 L186 I187 S189 G191 V192 G13 Q16 G17 I18 D37 I38 D60 I61 N87 A88 S89 I138 Y153 K157 P183 L185 I186 S188 G190 V191
BS02 4PL C S141 N142 T143 M151 Y154 H197 S140 N141 T142 M150 Y153 H196
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0050235 pyridoxal 4-dehydrogenase activity
Biological Process
GO:0042820 vitamin B6 catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3rwb, PDBe:3rwb, PDBj:3rwb
PDBsum3rwb
PubMed
UniProtQ988B7|PLDH_RHILO Pyridoxal 4-dehydrogenase (Gene Name=pldh-t)

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