Structure of PDB 3rnn Chain C

Receptor sequence
>3rnnC (length=258) Species: 9606 (Homo sapiens) [Search protein sequence]
KTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKL
TIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFS
KPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIA
VFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQR
KPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNK
WWYDKGEC
3D structure
PDB3rnn Structural and functional analysis of two new positive allosteric modulators of GluA2 desensitization and deactivation.
ChainC
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 RNN C P105 K218 G219 L239 N242 P102 K215 G216 L236 N239
BS02 GLU C Y61 L90 T91 R96 L138 G141 S142 T143 E193 Y58 L87 T88 R93 L135 G138 S139 T140 E190
BS03 ZN C E42 H46 E39 H43
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:3rnn, PDBe:3rnn, PDBj:3rnn
PDBsum3rnn
PubMed21543522
UniProtP42262|GRIA2_HUMAN Glutamate receptor 2 (Gene Name=GRIA2)

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