Structure of PDB 3rae Chain C

Receptor sequence
>3raeC (length=208) Species: 1313 (Streptococcus pneumoniae) [Search protein sequence]
GKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQAILPLRGKVINTA
KAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDADTDGAH
IQTLLLTFFYRYMRPLVEAGHVYIALPPLYKYAWTDGELEELRKLQRYKG
LGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGDKVEPRRKW
IEDNVKFT
3D structure
PDB3rae Structure of a quinolone-stabilized cleavage complex of topoisomerase IV from Klebsiella pneumoniae and comparison with a related Streptococcus pneumoniae complex.
ChainC
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.6.2.2: DNA topoisomerase (ATP-hydrolyzing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C E433 D510 E20 D97
BS02 dna C I460 N461 K464 N473 H513 V626 R629 I47 N48 K51 N60 H100 V194 R197
BS03 dna C D435 S436 D22 S23
BS04 MG C D506 D508 D93 D95
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0005524 ATP binding
Biological Process
GO:0006265 DNA topological change

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Molecular Function
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Biological Process
External links
PDB RCSB:3rae, PDBe:3rae, PDBj:3rae
PDBsum3rae
PubMed27050128
UniProtQ59961|PARE_STRPN DNA topoisomerase 4 subunit B (Gene Name=parE)

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