Structure of PDB 3r6s Chain C

Receptor sequence
>3r6sC (length=224) Species: 1718 (Corynebacterium glutamicum) [Search protein sequence]
GVQEILSRAGIFQGVDPTAVNNLIQDMETVRFPRGATIFDEGEPGDRLYI
ITSGKVKLARHAPDGRENLLTIMGPSDMFGELSIFDPGPRTSSAVCVTEV
HAATMNSDMLRNWVADHPAIAEQLLRVLARRLRRTNASLADLIFTDVPGR
VAKTLLQLANRFGTQEAGALRVNHDLTQEEIAQLVGASRETVNKALATFA
HRGWIRLEGKSVLIVDTEHLARRA
3D structure
PDB3r6s Crystal structure of GlxR transcription factor from Corynebacterium glutamicum with cAMP
ChainC
Resolution2.38 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CMP C F41 L60 L72 F81 G82 E83 L84 S85 R92 T93 R133 F39 L58 L70 F79 G80 E81 L82 S83 R90 T91 R131
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0001216 DNA-binding transcription activator activity
GO:0001217 DNA-binding transcription repressor activity
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0016301 kinase activity
GO:0030552 cAMP binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0016310 phosphorylation
GO:0045892 negative regulation of DNA-templated transcription
GO:0045893 positive regulation of DNA-templated transcription
GO:2000874 regulation of glyoxylate cycle
Cellular Component
GO:0005829 cytosol
GO:0032993 protein-DNA complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3r6s, PDBe:3r6s, PDBj:3r6s
PDBsum3r6s
PubMed
UniProtQ79VI7|CRPL_CORGL CRP-like cAMP-activated global transcriptional regulator (Gene Name=glxR)

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