Structure of PDB 3r5m Chain C

Receptor sequence
>3r5mC (length=213) Species: 9606 (Homo sapiens) [Search protein sequence]
EDMPVERILEAELAVENDPVTNICQAADKQLFTLVEWAKRIPHFSELPLD
DQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAI
FDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREK
VYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDT
PIDTFLMEMLEAP
3D structure
PDB3r5m Molecular determinants of magnolol targeting both RXR(alpha) and PPAR(gamma).
ChainC
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C F277 V280 K284 L294 V298 T449 F450 E453 F32 V35 K39 L49 V53 T204 F205 E208
BS02 MLO C I268 A272 N306 L309 F313 C432 L436 I23 A27 N61 L64 F68 C187 L191
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003707 nuclear steroid receptor activity
GO:0008270 zinc ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3r5m, PDBe:3r5m, PDBj:3r5m
PDBsum3r5m
PubMed22140563
UniProtP19793|RXRA_HUMAN Retinoic acid receptor RXR-alpha (Gene Name=RXRA)

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