Structure of PDB 3q0g Chain C

Receptor sequence
>3q0gC (length=255) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
MTYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATELDDDPDIG
AIIITGSAKAFAAGADIKEMADLTFADAFTADFFATWGKLAAVRTPTIAA
VAGYALGGGCELAMMCDVLIAADTAKFGQPEIKLGVLPGMGGSQRLTRAI
GKAKAMDLILTGRTMDAAEAERSGLVSRVVPADDLLTEARATATTISQMS
ASAARMAKEAVNRAFESSLSEGLLYERRLFHSAFATEDQSEGMAAFIEKR
APQFT
3D structure
PDB3q0g Crystal Structure of the Prokaryotic Crotonase
ChainC
Resolution2.38 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) A65 M70 T80 F84 G108 E111 P130 E131 V136 P138 G139 L224 F234
Catalytic site (residue number reindexed from 1) A65 M70 T80 F84 G108 E111 P130 E131 V136 P138 G139 L224 F234
Enzyme Commision number 4.2.1.17: enoyl-CoA hydratase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COA C L25 A63 I67 K68 Y104 P130 E131 L134 L25 A63 I67 K68 Y104 P130 E131 L134
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004300 enoyl-CoA hydratase activity
GO:0016829 lyase activity
GO:0016836 hydro-lyase activity
Biological Process
GO:0006631 fatty acid metabolic process
GO:0006635 fatty acid beta-oxidation
Cellular Component
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3q0g, PDBe:3q0g, PDBj:3q0g
PDBsum3q0g
PubMed
UniProtP9WNN9|ECHA8_MYCTU Probable enoyl-CoA hydratase EchA8 (Gene Name=echA8)

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