Structure of PDB 3pk1 Chain C

Receptor sequence
>3pk1C (length=137) Species: 9606 (Homo sapiens) [Search protein sequence]
SLYRQSLEIISRYLREQATGTSRKALETLRRVGDGVQRNHETAFQGMLRK
LDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQE
SCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHV
3D structure
PDB3pk1 Mutation to Bax beyond the BH3 domain disrupts interactions with pro-survival proteins and promotes apoptosis
ChainC
Resolution2.486 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C H224 M231 K234 H252 V253 D256 N260 G262 R263 T266 F318 F319 H40 M47 K50 H68 V69 D72 N76 G78 R79 T82 F134 F135
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:3pk1, PDBe:3pk1, PDBj:3pk1
PDBsum3pk1
PubMed21199865
UniProtQ07820|MCL1_HUMAN Induced myeloid leukemia cell differentiation protein Mcl-1 (Gene Name=MCL1)

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