Structure of PDB 3pgx Chain C

Receptor sequence
>3pgxC (length=270) Species: 1770 (Mycobacterium avium subsp. paratuberculosis) [Search protein sequence]
GSLQGRVAFITGAARGQGRSHAVRLAAEGADIIACDICAPVSASVTYAPA
SPEDLDETARLVEDQGRKALTRVLDVRDDAALRELVADGMEQFGRLDVVV
ANAGVLSWGRVWELTDEQWDTVIGVNLTGTWRTLRATVPAMIEAGNGGSI
VVVSSSAGLKATPGNGHYSASKHGLTALTNTLAIELGEYGIRVNSIHPYS
VETPMIEPEAMMEIFARHPSFVHSFPPMPVQPNGFMTADEVADVVAWLAG
DGSGTLTGTQIPVDKGALKY
3D structure
PDB3pgx Mycofactocin-associated mycobacterial dehydrogenases with non-exchangeable NAD cofactors.
ChainC
Resolution1.85 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) G22 S161 Y174 K178
Catalytic site (residue number reindexed from 1) G16 S155 Y168 K172
Enzyme Commision number 1.-.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD C G18 R21 G22 Q23 D42 I43 A56 D81 V82 N108 A109 G110 V111 V131 V159 S161 Y174 K178 P204 V207 T209 M211 I212 G12 R15 G16 Q17 D36 I37 A50 D75 V76 N102 A103 G104 V105 V125 V153 S155 Y168 K172 P198 V201 T203 M205 I206
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

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Molecular Function
External links
PDB RCSB:3pgx, PDBe:3pgx, PDBj:3pgx
PDBsum3pgx
PubMed28120876
UniProtQ73SC8|Y4146_MYCPA Uncharacterized NAD-dependent oxidoreductase MAP_4146 (Gene Name=MAP_4146)

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