Structure of PDB 3osa Chain C

Receptor sequence
>3osaC (length=230) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYSMMGLLTNLADRELVHMINWAKR
VPGFVDLTRHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRN
QGEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTL
KSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRH
MSNKGMEHLYSMKCKNVVPSYDLLLEMLDA
3D structure
PDB3osa Coupling of receptor conformation and ligand orientation determine graded activity.
ChainC
Resolution2.296 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 KN3 C L346 E353 I424 L428 L33 E40 I108 L112
External links
PDB RCSB:3osa, PDBe:3osa, PDBj:3osa
PDBsum3osa
PubMed20924370
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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