Structure of PDB 3o37 Chain C

Receptor sequence
>3o37C (length=176) Species: 9606 (Homo sapiens) [Search protein sequence]
PNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDL
SKPEVEYDCEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPL
TVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFN
EPDSEVANAGIKLENYFEELLKNLYP
3D structure
PDB3o37 TRIM24 links a non-canonical histone signature to breast cancer.
ChainC
Resolution2.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C N825 E826 D827 W828 Q833 N834 G835 E837 L838 L839 C840 C841 F860 P861 G863 N2 E3 D4 W5 Q10 N11 G12 E14 L15 L16 C17 C18 F37 P38 G40
BS02 peptide C D934 E978 D104 E148
BS03 ZN C C829 C832 H849 C852 C6 C9 H26 C29
BS04 ZN C C841 C844 C867 C870 C18 C21 C44 C47
External links
PDB RCSB:3o37, PDBe:3o37, PDBj:3o37
PDBsum3o37
PubMed21164480
UniProtO15164|TIF1A_HUMAN Transcription intermediary factor 1-alpha (Gene Name=TRIM24)

[Back to BioLiP]