Structure of PDB 3nd6 Chain C

Receptor sequence
>3nd6C (length=152) Species: 1351 (Enterococcus faecalis) [Search protein sequence]
MRKIALFPGSFDPMTNGHLNLIERSAKLFDEVIIGVFILFTPEEKKYLIE
EATKEMPNVRVIMQETQLTVESAKSLGANFLIRGIRNVKDYEYEKDIAKM
NQHLAPEIETVFLLAEEPYAHVSSSLLKEVLRFGGDVSDYLPPNIYHALK
QK
3D structure
PDB3nd6 Crystal structure of phosphopantetheine adenylyltransferase from Enterococcus faecalis in the ligand-unbound state and in complex with ATP and pantetheine
ChainC
Resolution2.3 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H18 R92 S130
Catalytic site (residue number reindexed from 1) H18 R86 S124
Enzyme Commision number 2.7.7.3: pantetheine-phosphate adenylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP C F7 G9 G17 H18 L21 R89 G90 R92 E100 A121 Y125 S129 S130 S131 F7 G9 G17 H18 L21 R83 G84 R86 E94 A115 Y119 S123 S124 S125
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004595 pantetheine-phosphate adenylyltransferase activity
GO:0005524 ATP binding
GO:0016779 nucleotidyltransferase activity
Biological Process
GO:0009058 biosynthetic process
GO:0015937 coenzyme A biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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External links
PDB RCSB:3nd6, PDBe:3nd6, PDBj:3nd6
PDBsum3nd6
PubMed21912874
UniProtQ831P9|COAD_ENTFA Phosphopantetheine adenylyltransferase (Gene Name=coaD)

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