Structure of PDB 3n84 Chain C

Receptor sequence
>3n84C (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]
MKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGND
VQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQV
PQQPTYVQA
3D structure
PDB3n84 Thermodynamic and Structural Effects of Macrocyclization as a Constraining Method in Protein-Ligand Interactions.
ChainC
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide C R67 R86 S88 S90 S96 Q106 H107 F108 K109 L120 W121 R13 R32 S34 S36 S42 Q52 H53 F54 K55 L66 W67
BS02 MG C V122 V123 V68 V69
External links
PDB RCSB:3n84, PDBe:3n84, PDBj:3n84
PDBsum3n84
PubMed21116482
UniProtP62993|GRB2_HUMAN Growth factor receptor-bound protein 2 (Gene Name=GRB2)

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