Structure of PDB 3lo5 Chain C

Receptor sequence
>3lo5C (length=155) Species: 9606 (Homo sapiens) [Search protein sequence]
MTEYKLVVVGAGGVGKNALTIQLIQNHSYRKQVVIDGETCLLDILDTAGQ
EEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPM
VLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVR
EIRQH
3D structure
PDB3lo5 Structure of the Dominant Negative S17N Mutant of Ras
ChainC
Resolution2.568 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP C G13 V14 G15 K16 N17 A18 N116 K117 D119 L120 S145 A146 G13 V14 G15 K16 N17 A18 N105 K106 D108 L109 S134 A135
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3lo5, PDBe:3lo5, PDBj:3lo5
PDBsum3lo5
PubMed20131908
UniProtP01112|RASH_HUMAN GTPase HRas (Gene Name=HRAS)

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