Structure of PDB 3kl8 Chain C

Receptor sequence
>3kl8C (length=256) Species: 6239 (Caenorhabditis elegans) [Search protein sequence]
KFSDNYDVKEELSVVRRCVHKTTGLEFAAKIINTDFQKLEREARICRKLQ
HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQ
ILESIAYCHSNGIVHRNLKPENLLLASKAKGAAVKLADFGLAIEVNDSEA
WHGFAGTPGYLSPEVLKKDPYSKPVDIWACGVILYILLVGYPPFWDEDQH
RLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVNPKKRITADQALKVP
WICNRE
3D structure
PDB3kl8 Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation.
ChainC
Resolution3.372 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N135 K137 E139 N140 D156 T175
Catalytic site (residue number reindexed from 1) N117 K119 E121 N122 D138 T157
Enzyme Commision number 2.7.11.17: calcium/calmodulin-dependent protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C E96 F98 K137 E139 D156 F172 A173 G174 T175 G208 P210 P211 W213 D230 E235 E78 F80 K119 E121 D138 F154 A155 G156 T157 G190 P192 P193 W195 D212 E217
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:3kl8, PDBe:3kl8, PDBj:3kl8
PDBsum3kl8
PubMed20139983
UniProtO62305|KCC2D_CAEEL Calcium/calmodulin-dependent protein kinase type II (Gene Name=unc-43)

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