Structure of PDB 3k9l Chain C

Receptor sequence
>3k9lC (length=158) Species: 9606 (Homo sapiens) [Search protein sequence]
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEFDPTIEDSYRKQVVIDGET
CLLDILDTAGDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDD
VPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYT
LVREIRQH
3D structure
PDB3k9l Allosteric modulation of H-Ras GTPase
ChainC
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GNP C G13 G15 K16 S17 A18 F28 D30 G60 N116 K117 D119 S145 A146 K147 G13 G15 K16 S17 A18 F28 D30 G60 N108 K109 D111 S137 A138 K139
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:3k9l, PDBe:3k9l, PDBj:3k9l
PDBsum3k9l
PubMed
UniProtP01112|RASH_HUMAN GTPase HRas (Gene Name=HRAS)

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