Structure of PDB 3k8x Chain C

Receptor sequence
>3k8xC (length=675) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
EWLQPKRYKAHLMGTTYVYDFPELFRQASSSQWKNFSADVKLTDDFFISN
ELIEDENGELTEVEREPGANAIGMVAFKITVKTPEYPRGRQFVVVANDIT
FKIGSFGPQEDEFFNKVTEYARKRGIPRIYLAANSGARIGMAEEIVPLFQ
VAWNDAANPDKGFQYLYLTSEGMETLKKFDKENSVLTERTVINGEERFVI
KTIIGSEDGLGVECLRGSGLIAGATSRAYHDIFTITLVTCRSVGIGAYLV
RLGQRAIQVEGQPIILTGAPAINKMLGREVYTSNLQLGGTQIMYNNGVSH
LTAVDDLAGVEKIVEWMSYVPAKRNMPVPILETKDTWDRPVDFTPTNDET
YDVRWMIEGRETESGFEYGLFDKGSFFETLSGWAKGVVVGRARLGGIPLG
VIGVETRTVENLIPADPANPNSAETLIQEPGQVWHPNSAFKTAQAINDFN
NGEQLPMMILANWRGFSGGQRDMFNEVLKYGSFIVDALVDYKQPIIIYIP
PTGELRGGSWVVVDPTINADQMEMYADVNARAGVLEPQGMVGIKFRREKL
LDTMNRLDDKYRELLPIYGQISLQFADLHDRSSRMVAKGVISKELEWTEA
RRFFFWRLRRRLNEEYLIKRLSHQVGEASRLEKIARIRSWYPASVDHEDD
RQVATWIEENYKTLDDKLKGLKLES
3D structure
PDB3k8x A different mechanism for the inhibition of the carboxyltransferase domain of acetyl-coenzyme A carboxylase by tepraloxydim.
ChainC
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.4.14: biotin carboxylase.
6.4.1.2: acetyl-CoA carboxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 B89 C G1997 G1998 V2001 V2002 G507 G508 V511 V512
BS02 B89 C G1626 A1627 G1734 I1735 Y1738 G136 A137 G244 I245 Y248
Gene Ontology
Molecular Function
GO:0003989 acetyl-CoA carboxylase activity
GO:0016874 ligase activity

View graph for
Molecular Function
External links
PDB RCSB:3k8x, PDBe:3k8x, PDBj:3k8x
PDBsum3k8x
PubMed19926852
UniProtQ00955|ACAC_YEAST Acetyl-CoA carboxylase (Gene Name=ACC1)

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