Structure of PDB 3k8d Chain C

Receptor sequence
>3k8dC (length=246) Species: 562 (Escherichia coli) [Search protein sequence]
SFVVIIPARYASTRLPGKPLVDINGKPMIVHVLERARESGAERIIVATDH
EDVARAVEAAGGEVCMTRADHQSGTERLAEVVEKCAFSDDTVIVNVQGDE
PMIPATIIRQVADNLAQRQVGMATLAVPIHNAEEAFNPNAVKVVLDAEGY
ALYFSRATIPWDRDRFAEGLETVGDNFLRHLGIYGYRAGFIRRYVNWQPS
PLEHIEMLEQLRVLWYGEKIHVAVAQEVPGTGVDTPEDLERVRAEM
3D structure
PDB3k8d Structure-based mechanism of CMP-2-keto-3-deoxymanno-octulonic acid synthetase: convergent evolution of a sugar-activating enzyme with DNA/RNA polymerases
ChainC
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.38: 3-deoxy-manno-octulosonate cytidylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CTP C P8 A9 R10 S13 T14 R15 K19 H72 Q73 S74 G75 R78 Q98 G99 D100 P7 A8 R9 S12 T13 R14 K18 H71 Q72 S73 G74 R77 Q97 G98 D99
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0005515 protein binding
GO:0008690 3-deoxy-manno-octulosonate cytidylyltransferase activity
GO:0016779 nucleotidyltransferase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0009103 lipopolysaccharide biosynthetic process
GO:0019294 keto-3-deoxy-D-manno-octulosonic acid biosynthetic process
GO:0033468 CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3k8d, PDBe:3k8d, PDBj:3k8d
PDBsum3k8d
PubMed19815542
UniProtP04951|KDSB_ECOLI 3-deoxy-manno-octulosonate cytidylyltransferase (Gene Name=kdsB)

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