Structure of PDB 3k4m Chain C

Receptor sequence

>3k4mC (length=574) Species: 230624 (Trametes ochracea)

KYDVVIVGSGPIGCTYARELVGAGYKVAMFDIGEIDSGLKIGAHKKNTVE
YQKNIDKFVNVIQGQLMSVSVPVNTLVVDTLSPTSWQASTFFVRNGSNPE
QDPLRNLSGQAVTRVVGGMSTHWTCATPRFDREQRPLLVKDDADADDAEW
DRLYTKAESYFQTGTDQFKESIRHNLVLNKLTEEYKGQRDFQQIPLAATR
RSPTFVEWSSANTVFDLQNRPNTDAPEERFNLFPAVACERVVRNALNSEI
ESLHIHDLISGDRFEIKADVYVLTAGAVHNTQLLVNSGFGQLGRPNPANP
PELLPSLGSYITEQSLVFCQTVMSTELIDSVKSDMTIRGTPGELTYSVTY
TPGASTNKHPDWWNEKVKNHMMQHQEDPLPIPFEDPEPQVTTLFQPSHPW
HTQIHRDAFSWGAVQQSIDSRLIVDWRFFGRTEPKEENKLWFSDKITDAY
NMPQPTFDFRFPAGRTSKEAEDMMTDMCVMSAKIGGFLPGSLPQFMEPGL
VLHLGGTHRMGFDEKEDNCCVNTDSRVFGFKNLFLGGCGNIPTAYGANPT
LTAMSLAIKSCEYIKQNFTPSPFT

3D structure

• PDB: 3k4m Importance of the gating segment in the substrate-recognition loop of pyranose 2-oxidase.
• Chain: C
• Resolution: 2.2 Å

Enzymatic activity

• Enzyme Commision number: 1.1.3.10: pyranose oxidase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	C	V52 G55 P56 I57 D76 I77 T158 R159 V160 G163 M164 H167 W168 T169 C170 A171 C283 A320 H324 L547 N593 T595	V7 G10 P11 I12 D31 I32 T113 R114 V115 G118 M119 H122 W123 T124 C125 A126 C238 A275 H279 L502 N548 T550
BS02	SHG	C	T169 Q448 D452 V546 H548 N593	T124 Q403 D407 V501 H503 N548

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0016491 oxidoreductase activity
• GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
• GO:0050233 pyranose oxidase activity
• GO:0050660 flavin adenine dinucleotide binding

Cellular Component

• GO:0042597 periplasmic space

External links

• PDB: RCSB:3k4m, PDBe:3k4m, PDBj:3k4m
• PDBsum: 3k4m
• PubMed: 20528921
• UniProt: Q7ZA32